The therapeutic journey of pyridazinone

Eur J Med Chem. 2016 Nov 10:123:256-281. doi: 10.1016/j.ejmech.2016.07.061. Epub 2016 Jul 27.

Abstract

Pyridazinones have drawn a substantial attention within the field of research analysis and development. The moiety is a subject matter of intensive research because of its wide spectrum of biological activities and therapeutic applications. The synthesis of pyridazinone and investigation of their chemical and biological activities have gained additional importance in recent years. In this review, we have compiled and discussed various biological and therapeutic potential of pyridazinone derivatives.

Keywords: Anti-inflammatory and analgesic; Anticancer; Antiviral; Biological activity; Heterocyclic; Pyridazinone.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Pyridazines / pharmacology*
  • Pyridazines / therapeutic use

Substances

  • Pyridazines